DiA Labeled Fluorescent Control Liposomes for Clophosome^® -A (Anionic)

Thefluorescent control liposomescontainthe lipophilic dye DiA incorporated in the bilayers. It has comparable physical and chemical attributes as for the Clophosome^® except noactive is encapsulated inside. It is used for tracking the cellular uptake of the liposomes by common methods like confocal, FACS, etc.

The lipophilic aminostyryl probeDiAinserts into lipid membranes with its two alkyl tails and its fluorophore oriented parallel to the phospholipid acyl chain. When this dialkylaminostyryl probe binds to membranes, it exhibits a strong fluorescence enhancement; its fluorescence in water is minimal.

Specifications

Lipid composition:phosphatidylcholine,phosphatidylglycerol andcholesterol

Dye: 0.15 mM (0.12mg/mL)

Stability: 6 months for unopened vials

Storage: 2-8 ºC

'DiA';4-Di-16-ASP (4-(4-(Dihexadecylamino)styryl)-N-Methylpyridinium Iodide) (Invitrogen D-3883)