DiD Labeled Fluorescent Control Liposomes for Clophosome^® (Neutral)

Thefluorescent control liposomescontainthe lipophilic dye DiD incorporated in the bilayers. It has comparable physical and chemical attributes as for the Clophosome^® except noactive is encapsulated inside. It is used for tracking the cellular uptake of the liposomes by common methods like confocal, FACS, etc.

The far-red fluorescent, lipophilic carbocyanineDiDis a longer-wavelength DiI analog. It is an oil at room temperature and weakly fluorescent in water but highly fluorescent and quite photostable when incorporated into membranes. It has an extremely high extinction coefficient and short excited-state lifetimes (~1 nanosecond) in lipid environments.

Specifications

Lipid composition:phosphatidylcholine and cholesterol

Dye: 0.15 mM (0.14mg/mL)

Stability: 6 months for unopened vials

Storage: 2-8 ºC

'DiD'; DiIC18(5) oil (1,1'-Dioctadecyl-3,3,3',3'-Tetramethylindodicarbocyanine Perchlorate)(Invitrogen D-307)