DiRLabeledFluorescentControlliposomesforClophosome®(Neutral)
ThefluorescentcontrolliposomescontainthelipophilicdyeDiRincorporatedinthebilayers.IthascomparablephysicalandchemicalattributesasfortheClophosome®exceptnoClodronateencapsulatedinside.Itisusedfortrackingthecellularuptakeoftheliposomesbycommonmethodslikeconfocal,FACS,NIRimagingetc.
ThenearIRfluorescent,lipophiliccarbocyanineDiOC18(7)("DiR")isweaklyfluorescentinwaterbuthighlyfluorescentandquitephotostablewhenincorporatedintomembranes.ThesulfonategroupsincorporatedintothisDiIanalogimproveswatersolubility.Ithasanextremelyhighextinctioncoefficientandshortexcited-statelifetimes(~1nanosecond)inlipidenvironments.
Specifications
Lipidcomposition:phosphatidylcholineandcholesterol
Dye:0.15mM(0.15mg/mL)
StABIlity:6monthsforunopenedvials
Storage:2-8ºC
"DiR";(InvitrogenD-12731)DiIC18(7)(1,1"-Dioctadecyl-3,3,3",3"-TetramethylindotricarbocyanineIodide)
Ex/Em:750/780nm
CASNumber:n/a
